ABOUT US
“My goal is to translate fundamental immunological insights into clinical applications that decode the complexities of T1D and advance diagnostic, prophylactic, and therapeutic modalities.”
Dirk Homann, MD, PhD, MA
Dr. Dirk Homann is a physician and immunologist/virologist trained in Berlin, Boston, Paris, and La Jolla. He started his independent career at the University of Colorado, moved to Mount Sinai in New York in 2014 where he became a tenured Professor in 2019, and recently joined the DRI. Dr. Homann’s work focuses on T cell immunity in autoimmune and infectious diseases, with an emphasis on T1D. His research integrates T cell and pancreatic islet cell biology with the overarching aim to develop immunomodulatory strategies for T1D prevention and reversal.
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Dr. Homann’s research explores the generation, maintenance and modulation of protective and destructive T cell immunity, with a particular focus on T cell memory. In addition, much of his recent work leverages broad cross-disciplinary approaches to T1D biomarker discovery and invests in novel technology platforms for interrogation of pancreatic histopathology to better understand the natural history of T1D. Altogether, these efforts seek to improve T1D risk predictions and to identify suitable strategies for tailored preventive and therapeutic interventions.
Dr. Homann’s commitment to T1D research is inspired by a passion for advancing treatments that improve patients’ lives. Trained as a concert pianist, he enjoys making music, exploring art, literature, theater, and film, as well as skiing and sailing. He is also passionate about traveling and discovering new cultures, traditions, and languages.
“My goal is to translate fundamental immunological insights into clinical applications that decode the complexities of T1D and advance diagnostic, prophylactic, and therapeutic modalities.”
To leverage high-resolution imaging and advanced image analysis pipelines to unravel histopathological correlates of type 1 diabetes progression, enhancing our understanding of disease stages and informing targeted therapeutic interventions.

